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Phenotype Image Detail
Image
Caption Histological sections of male (A & B) and female (C & D) gonads are shown, comparing the gonads of wild type (A & C) and Fanclgcd/Fanclgcd mice (B & D). The homozygous mouse testis (B) contained groups of normal (N) and abnormal (A) seminferous tubules. The abnormal seminiferous tubules contained only large, vacuolated Sertoli cells. The homozygous mouse ovary (D) is much smaller than the normal ovary (C) and is relatively inactive, containing no developing follicles (F) and only a few, old corpora lutea (C). Also, a well-delineated hemorrhagic cyst is present in the upper-right quadrant of the homozygous ovary (D).
Copyright This image is from Pellas TC, Proc Natl Acad Sci U S A 1991 Oct 1;88(19):8787-91. Copyright 1991 National Academy of Sciences, U.S.A. J:21254
Associated
Alleles
Symbol Name
Fanclgcd Fanconi anemia, complementation group L; germ cell deficient
Associated
Genotypes
Allelic Composition Genetic Background
Fanclgcd/Fanclgcd involves: C57BL/6J * CBA/J

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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory