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| Caption | A: Photographs of wild type, Gba1tm1Rlp/Gba1tm1Rlp (center) and Gba1tm2Rlp/Gba1tm2Rlp (right) mice within 12 hours after birth. The arrow denotes the presence of milk in the stomach. Note the small size and wrinkled skin of the Gba1tm2Rlp/Gba1tm2Rlp mouse. The skin of the Gba1tm1Rlp/Gba1tm1Rlp mouse is less severely wrinkled. The bracket indicates the sites where skin samples were taken for the photomicrographs in B. B: Section of epidermis. Stratum corneum (SC) of Gba1tm1Rlp/Gba1tm1Rlp and Gba1tm2Rlp/Gba1tm2Rlp mice are compacted and less eosinophillic compared with the loosely packed eosinophillic SC in the wild type mouse. No significant differences are noted in the three other layers of the epidermis (EP) (Stratum basale, stratum spinosum and stratum granulosum) or the dermis (D). Magnification x150 | ||||||
| Copyright | This image is from Liu Y, Proc Natl Acad Sci U S A 1998 Mar 3;95(5):2503-8. Copyright 1998 National Academy of Sciences, U.S.A. J:46243 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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