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Phenotype Image Detail
Image
Caption Wild type (A) and Zfpm1tm1Sho/Zfpm1tm1Sho Tg(Gata1-Zfpm1)1Sho (B) embryos at E14.5 show edema and hemorrhage in the mutant. Transverse sections of wild type (C) and mutant (D) hearts at E14.5 show aorta and pulmonary trunk arising from the right ventricle in the mutant. Transverse sections of wild type (E) and mutant (F) hearts at E14.5 show a common AV valve with ventricular septal defect in the mutant. G: Section of the ventricular wall of a mutant embryo at E14.5. The arrow identifies a coronary vessel. Magnifications: A-F: x100; G: x400
Copyright This image is from Katz SG, Proc Natl Acad Sci U S A 2003 Nov 25;100(24):14030-5. Copyright 2003 National Academy of Sciences, U.S.A. J:99745
Associated
Alleles
Symbol Name
Tg(Gata1-Zfpm1)1Sho transgene insertion 1, Stuart Orkin
Zfpm1tm1Sho zinc finger protein, multitype 1; targeted mutation 1, Stuart Orkin
Associated
Genotypes
Allelic Composition Genetic Background
Tg(Gata1-Zfpm1)1Sho/0
Zfpm1tm1Sho/Zfpm1tm1Sho
involves: 129S1/Sv * C57BL/6N * CD-1

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory