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Phenotype Image Detail
Image
Caption Heart comparisons of wild type (left) and Actc1tm1Jll/Actc1tm1Jll Tg(Myh6-Actg2)1Jll mice (right) clearly show myocyte hypertrophy in the left ventricle of the rescued heart. Also note the thrombi occluding a highly dilated right atrium (bottom). Abbreviations: LV: left ventricle; RA: right atrium. Magnifications: Top: x15; Middle: x40; Bottom: x4
Copyright This image is from Kumar A, Proc Natl Acad Sci U S A 1997 Apr 29;94(9):4406-11. Copyright 1997 National Academy of Sciences, U.S.A. J:40165
Associated
Alleles
Symbol Name
Actc1tm1Jll actin, alpha, cardiac muscle 1; targeted mutation 1, James Lessard
Tg(Myh6-Actg2)1Jll transgene insertion 1, James L Lessard
Associated
Genotypes
Allelic Composition Genetic Background
Actc1tm1Jll/Actc1tm1Jll
Tg(Myh6-Actg2)1Jll/0 		involves: 129P2/OlaHsd * Black Swiss * FVB/N
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory