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Phenotype Image Detail
Image
Caption A: Whole animal contact radiographs of 17.5dpc mice (Faxitron X-Ray, Wheeling, IL). At this age no skeletal elements are detected by soft x-rays in the Runx2tm1Gss/Runx2tm1Gss (deltaC/deltaC) compared with wild type and Runx2tm1Gss/Runx2+ mice. B: Radiography of 6-wk mice to visualize phenotype of the heterozygote. Shown is a dorsal view of a wild type mouse with arrow pointing to the clavicle that is missing in the heterozygous mouse. C: Staining of skeletons from 17.5dpc and 18.5dpc embryos with Alizarin red to detect bone and Alcian blue to detect cartilage by standard procedures.
Copyright This image is from Choi JY, Proc Natl Acad Sci U S A 2001 Jul 17;98(15):8650-5. Copyright 2001 National Academy of Sciences, U.S.A. J:70461
Associated
Alleles
Symbol Name
Runx2tm1Gss runt related transcription factor 2; targeted mutation 1, Gary S Stein
Associated
Genotypes
Allelic Composition Genetic Background
Runx2tm1Gss/Runx2tm1Gss involves: 129S7/SvEvBrd * C57BL/6
Runx2tm1Gss/Runx2+ involves: 129S7/SvEvBrd * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory