About   Help   FAQ
Phenotype Image Detail
Image
Caption A: Large vascular lesion (arrow) visible on the surface of the brain of a 13 month old Ccm2Gt(RRG051)Byg/Ccm2+ mouse. B: Sectioning of the lesion reveals a mass of closely packed, tortuous blood vessels. C: Hemorrhaging visible of the surface of the brain of a 37 day old heterozygous mouse. D-F: Vascular malformations consisting of clusters of dilated blood vessels in the brain of a 37 day old mouse. G: Diffuse hemorrhage in the brain of the 37 day old mouse. H: Hemosiderin deposits (blue stain) present in the brain of the 37 day old mouse are indicative of chronic hemorrhaging. (B, D-G) Hematoxylin and eosin staining; (H) Prussian blue stain with nuclear fast red counterstain.
Copyright This image is from Plummer NW, Mamm Genome 2006 Feb;17(2):119-28 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:105314
Associated
Alleles
Symbol Name
Ccm2Gt(RRG051)Byg cerebral cavernous malformation 2; gene trap RRG051, BayGenomics
Associated
Genotypes
Allelic Composition Genetic Background
Ccm2Gt(RRG051)Byg/Ccm2+ involves: 129P2/OlaHsd * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/22/2024
MGI 6.24
The Jackson Laboratory