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| Caption | A: Wild type (left) and Tfap2aMhdador/Tfap2aMhdador (right) embryos at 18.5. The homozygous mutant embryos have smaller eyes (arrow) and abnormal facial structure in the form of a shorter and/or narrower snout. B-E: H & E staining of sections of E18.5 eyes from wild type (B), Tfap2aMhdador/Tcfap2a+ (C) and homozygous embryos (D & E). Homozygous mice show variability in ocular phenotype with adhesion of a smaller lens to the cornea (col) (D) or absencce of lens (E). The neuroretina (nr) is folded in some embryos (E) and occasionally anterior eye structures, such as the iris, and ciliary body, fail to form and instead devekop into a neuroretina (nr, E). | ||||
| Copyright | This image is from Ahituv N, Mamm Genome 2004 Jun;15(6):424-32 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:90701 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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