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| Caption | A & B: Hematoxylin and eosin staining of sections from the adrenal gland of wild type (left panels) and Mc2rtm1Dchi/Mc2rtm1Dchi mice. Ten week old male or 13 week old female homozygous mutant mice were analyzed. B: Higher magnification images of zG (zona glomerulosa), zF (zona fasciculata), and ME (medulla) shown in A. The white and black arrowheads in A indicate the border between zG/zF and cortical zone/ME, respectively. The brackets in B indicate thickness of the capsule, which was remarkably thicker in the mutant mice. C: Immunofluorescent detection of aldosterone synthase cytochrome P450 (P450aldo) and TH in the adrenal gland of wild type and mutant mice. Both enzymes were normally expressed in the mutant mice. Scale bars: 50um | ||||
| Copyright | This image is from Chida D, Proc Natl Acad Sci U S A 2007 Nov 13;104(46):18205-10. Copyright 2007 National Academy of Sciences, U.S.A. J:127445 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/22/2024 MGI 6.24 |
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