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| Caption | A-D: Wild type and Nfiatm1Rmg/Nfia+ Tg(Hoxb7-EGFP)33Cos newborns with megaureter (with extent of dilation indicated by two-headed arrow) (A, C) and partial ureteral duplication (arrow) in the Nfiatm1Rmg/Nfia+ Tg(Hoxb7-EGFP)33Cos (C). Higher power views of boxed areas in (A) and (C), showing distortion of the heterozygous mutant ureter at the UNJ (B & D); note that the vas deferens in the heterozygous male (C) is also GFP-positive. E & F: Abnormalities in the homozygous mutant newborns include proximal flexion of the ureter (E) and dysplastic kidney (F). Abbreviations: k, kidney; t, testis; ur, ureter. UNJ, ureterovesical junction; v, vas deferens | ||||||
| Copyright | This image is from Lu W, PLoS Genet 2007 May 25;3(5):e80, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:122749 | ||||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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