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Phenotype Image Detail
Image
Caption A: At E9.75 wild type and Mapk7tm1Jsca/Mapk7tm1Jsca yolk sacs contain blood islands (arrow). By E10.25 (B), the blood vessels found in wild type yolk sacs formed distinct large vessels which branched down into smaller vessels (arrow). In contrast, the surfaces of the mutant yolk sacs became pale, and did not show the branched blood vessels. At. E11.5 (C), mutant yolk sacs appeared intermittent with diffuse patches of red blood cells (arrow). The mutant embryos are pale and apparently devoid of blood circulation without a beating heart.
Copyright This image is from Yan L, BMC Dev Biol 2003 Dec 16;3():11, an open-access article, licensee BioMed Central Ltd. J:107620
Associated
Alleles
Symbol Name
Mapk7tm1Jsca mitogen-activated protein kinase 7; targeted mutation 1, J Simon C Arthur
Associated
Genotypes
Allelic Composition Genetic Background
Mapk7tm1Jsca/Mapk7tm1Jsca either: (involves: BALB/c) or (involves: C57BL/6)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory