About   Help   FAQ
Phenotype Image Detail
Image
Caption Hearts were fixed in formalin and paraffin sections prepared and stained with either hematoxylin and eosin (A & B) or trichrome (C-F) to highlight the interstitial fibrosis. Representative low-power views from a control heart (A) and individual binary transgenic hearts (B-D). Note the chamber dilatation (B & C) and marked variability in the extent of fibrosis (C & D) in binary hearts. Higher power views demonstrate the presence of scant residual myocytes in the most severe lesions (E & F).
Copyright This image is from Lee P, Proc Natl Acad Sci U S A 1998 Sep 15;95(19):11371-6. Copyright 1998 National Academy of Sciences, U.S.A. J:128617
Associated
Alleles
Symbol Name
Tg(Myh6-tTA)6Smbf transgene insertion 6, Section of Myocardial Biology - Fishman Lab
Tg(tetO-DTA)1Gfi transgene insertion 1, Glenn I Fishman
Associated
Genotypes
Allelic Composition Genetic Background
Tg(Myh6-tTA)6Smbf/0
Tg(tetO-DTA)1Gfi/0
involves: C57BL/6 * CBA

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory