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| Caption | A: The Avy allele carries an insertion of an intracisternal A-particle (IAP) retrotransposon in an antisense direction in agouti pseudoexon 1A. The Avy transcript originates from a cryptic promoter in the 5' LTR of the IAP and is spliced to agouti coding exons 2,3 and 4, which encode agouti signaling protein (ASP). When the IAP is silent, agouti is transcribed from hair cycle specific promoters in exons 1B and 1C. B: Avy/a phenotypes are scored from 1 to 5 based on coat color. Fully yellow mice are scored as 1, and fully agouti mice are scored as 5. Phenotypes of mosaic mice range from mostly yellow (2) to mottled yellow/agouti (3) to mostly agouti (4). | ||||
| Copyright | This image is from Cropley JE, Proc Natl Acad Sci U S A 2006 Nov 14;103(46):17308-12. Copyright 2006 National Academy of Sciences, U.S.A. J:117156 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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