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Phenotype Image Detail
Image
Caption Gross morphology of yolk sac (C,D) and embryo proper (E, F) of wild type (left) and Acvrl1tm1Enl/Acvrl1tm1Enl embryos (right) at E9.5 (C,E) and E10.5 (D,F). Arrows with asterisks (C) indicate yolk sac blood vessels. Arrows (F) indicate clumps of blood cells in the mutant embryos. pc, pericardium. (G, H) Histological analysis of E9.5 wild type (G) and mutant (H) embryos in decidua. In the mutant yolk sac, blood, and endothelial cells (EC) are present, but vessels are enlarged (H). bc, blood cells; d, decidua; en, endothelium.
Copyright This image is from Oh SP, Proc Natl Acad Sci U S A 2000 Mar 14;97(6):2626-31. Copyright 2000 National Academy of Sciences, U.S.A. J:61177
Associated
Alleles
Symbol Name
Acvrl1tm1Enl activin A receptor, type II-like 1; targeted mutation 1, En Li
Associated
Genotypes
Allelic Composition Genetic Background
Acvrl1tm1Enl/Acvrl1tm1Enl involves: C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory