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Phenotype Image Detail
Image
Caption Hematoxylin and eosin staining of wild type (A-D) and Pdpntm1Mcws/Pdpntm1Mcws (E-H) lungs at E11.5, 15.5, 18.5 and 19.5 respectively. Scale bar: 100um. Wild type (I-K) and mutant mouse lungs at E15.5, E18.5 and E19.5. Scale bar: 25um. Similar lung morphology is observed in wild type and mutant mouse lungs at E11.5 and E15.5. The phenotype is more severe after E18.5. Thereafter, the lungs exhibit narrower airspaces and thicker mesenchyme. Abbreviations: P, pleura; E, epithelium; A, alveolar space.
Copyright This image is from Millien G, BMC Dev Biol 2006;6():35, an open-access article, licensee BioMed Central Ltd. J:119680
Associated
Alleles
Symbol Name
Pdpntm1Mcws podoplanin; targeted mutation 1, Mary C Williams
Associated
Genotypes
Allelic Composition Genetic Background
Pdpntm1Mcws/Pdpntm1Mcws involves: 129S6/SvEvTac

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory