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Phenotype Image Detail
Image
Caption Paraffin sections were stained with hematoxylin and eosin. A: Section through mouse dorsolateral prostate of Tg(TRAMP)8247Ng/0 male at 10 weeks of age shows glands with intraepithelial hyperplasia. B: Section through dorsolateral prostate of 22 week old male shows predominantly hyperplastic glandular epithelium. C: Section through dorsolateral prostate of 40 week old male shows cribriform and flattened ducts with poorly differentiated adenocarcinoma. D: Section through dorsolateral prostate of 20 week old male shows poorly differentiated invasive adencarcinoma with few remaining ductal structures.
Copyright This image is from Greenberg NM, Proc Natl Acad Sci U S A 1995 Apr 11;92(8):3439-43. Copyright 1995 National Academy of Sciences, U.S.A. J:65303
Associated
Alleles
Symbol Name
Tg(TRAMP)8247Ng transgene insertion 8247, Norman M Greenberg
Associated
Genotypes
Allelic Composition Genetic Background
Tg(TRAMP)8247Ng/0 involves: C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory