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Phenotype Image Detail
Image
Caption The lethal skin phenotype in the newborn Gba1tm2Karl/Gba1tm2Karl mouse (upper left) is similar to other defective Gba mice. Littermate control (upper right). (Lower) Gba1tm2Karl/Gba1tm2Karl Tg(KRT14-cre)8Brn/? mouse at end stage (constant paralysis around 2 weeks old).
Copyright This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
Associated
Alleles
Symbol Name
Gba1tm2Karl glucosylceramidase beta 1; targeted mutation 2, Stefan Karlsson
Tg(KRT14-cre)8Brn transgene insertion 8, Anton Berns
Associated
Genotypes
Allelic Composition Genetic Background
Gba1tm2Karl/Gba1tm2Karl involves: 129S1/Sv * 129X1/SvJ
Gba1tm2Karl/Gba1tm2Karl
Tg(KRT14-cre)8Brn/?
involves: 129S1/Sv * 129X1/SvJ * FVB/N

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory