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Phenotype Image Detail
Image
Caption A: Mortality in C1galt1ptl1/C1galt1ptl1 and C1galt1ptl1/C1galt1ptl1 Rag1tm1Bal/Rag1tm1Bal mice. B: Histological sections of kidneys from sick C1galt1ptl1/C1galt1ptl1 or C1galt1ptl1/C1galt1ptl1 Rag1tm1Bal/Rag1tm1Bal mice and healthy controls illustrating the extensive inflammatory infiltration, loss of glomeruli, and tubular disorganization in the C1galt1ptl1/C1galt1ptl1 mouse kidneys.
Copyright This image is from Alexander WS, Proc Natl Acad Sci U S A 2006 Oct 31;103(44):16442-7. Copyright 2006 National Academy of Sciences, U.S.A. J:115272
Associated
Alleles
Symbol Name
C1galt1ptl1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; ptl1
Rag1tm1Bal recombination activating 1; targeted mutation 1, David Baltimore
Associated
Genotypes
Allelic Composition Genetic Background
C1galt1ptl1/C1galt1ptl1 C57BL/6-C1galt1ptl1
C1galt1ptl1/C1galt1ptl1
Rag1tm1Bal/Rag1tm1Bal 		involves: 129S4/SvJae * C57BL/6
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory