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Phenotype Image Detail
Image
Caption A: Western blot analysis of STAT3 in forebrain, hypothalamus, and cerebellum in wild type (WT) and Stat3tm1Flv/Stat3tm1Flv Tg(Nes-cre)1Kln/0 mice (KO) mice. The blot was stripped and reprobed with a STAT1 Ab as a control. B: Heterozygous and obese homozygous mice compared to a Leprdb/Leprdb (db/db) mutant. C: NMR imaging by using a minispec MQ10 analyzed (Bruker, Woodlands, TX) of wild type, KO, and db/db mice (n=4) showing total fat and lean mass as well as free fluid. Data are given as percentage of total body weight.
Copyright This image is from Gao Q, Proc Natl Acad Sci U S A 2004 Mar 30;101(13):4661-6. Copyright 2004 National Academy of Sciences, U.S.A. J:89242
Associated
Alleles
Symbol Name
Stat3tm1Flv signal transducer and activator of transcription 3; targeted mutation 1, Richard A Flavell
Tg(Nes-cre)1Kln transgene insertion 1, Rudiger Klein
Associated
Genotypes
Allelic Composition Genetic Background
Leprdb/Leprdb involves: C57BLKS/J
Stat3tm1Flv/Stat3tm1Flv
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * SJL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory