Phenotype Image Detail

Image

Caption

(A) Morphology and (B) skeleton of 21 day old wild type (WT), Fgfr3^tm3.1Cxd/Fgfr3⁺ (369/+), and Fgfr3^tm3.1Cxd/Fgfr3^tm3.1Cxd (369/369) mice. Notice dome-shaped heads in heterozygous and homozygous mice (arrows). (C) Quantitative measurements of tail length of mice with 3 genotypes. Each point represents data from an average of 5 mice. Standard deviation is less than +/- 5%. (D) X-ray of homozygous and wild type mice. Notice the reduced bone density in homozygous mutant mice. F, femur; T, tibia.

This image is from Chen L, J Clin Invest 1999 Dec;104(11):1517-25 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:69849

Associated
Alleles

Symbol	Name
Fgfr3^tm3.1Cxd	fibroblast growth factor receptor 3; targeted mutation 3.1, Chu-Xia Deng

Associated
Genotypes

Allelic Composition	Genetic Background
Fgfr3^tm3.1Cxd/Fgfr3^tm3.1Cxd	involves: 129S6/SvEvTac
Fgfr3^tm3.1Cxd/Fgfr3⁺	involves: 129S6/SvEvTac

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