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Phenotype Image Detail
Image
Caption Electron microscopy of heart and skeletal muscle in Gaatm1Rabn/Gaatm1Rabn mice at different stages. Top panel, skeletal muscle, (A,B and C) at 3, 10 and 15 weeks, respectively (x9,000). Middle panel, heart, (D,E and F) at 3, 10 and 15 weeks, respectively (x9,000). Bottom panel, muscle, (G) at 15 weeks (x30,000); heart (H and I) at 3 and 15 weeks, respectively (x30,000). Note different degree of glycogen density in heart lysosomes at 3 and 15 weeks; at 15 weeks, all lysosomes are densely packed with glycogen.
Copyright This image is from Raben N, J Biol Chem 1998 Jul 24;273(30):19086-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:48839
Associated
Alleles
Symbol Name
Gaatm1Rabn glucosidase, alpha, acid; targeted mutation 1, Nina Raben
Associated
Genotypes
Allelic Composition Genetic Background
Gaatm1Rabn/Gaatm1Rabn involves: 129X1/SvJ * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory