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Phenotype Image Detail
Image
Caption A-D: Incisors of 3 week old (A and B) and 12 month old (C and D) Sp6tm1Yoya/Sp6+ (+/-, A and C) and Sp6tm1Yoya/Sp6tm1Yoya (-/-, B and D) mice. B: Incisor development of 3 week old homozygous mice is delayed. D: 12 month old homozygous mice had an excess number of incisors with a mineral defect. E-H: Radiogram analysis of 6 month old mouse heads from heterozygous (E and F, enlarged) and homozygous mice (G and H, enlarged). asterisk, molars; in, incisors; arrowheads, al, alveolar bones (arrowheads); rt, roots.
Copyright This image is from Nakamura T, J Biol Chem 2008 Feb 22;283(8):4825-33 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:132157
Associated
Alleles
Symbol Name
Sp6tm1Yoya trans-acting transcription factor 6; targeted mutation 1, Yoshihiko Yamada
Associated
Genotypes
Allelic Composition Genetic Background
Sp6tm1Yoya/Sp6tm1Yoya B6.129-Sp6tm1Yoya

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory