Phenotype Image Detail

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Phenotype Image Detail

Image

Caption

A: Enlarged lymph nodes (top) and spleen (bottom) from either Myc^tm1Lbox/Myc^tm1Lbox or Myc^tm1Lbox/Myc⁺ mouse with lymphoma. B: Hematoxylin and eosin staining of wild type spleen (4x magnification). C: Hematoxylin and eosin staining of spleen from a mutant mouse with lymphoma (4x magnification). D: Higher magnification (40x) of mutant spleen. Infiltration of lymphoma into lung (E) and kidney (F). 40x magnification.

This image is from Wang J, J Biol Chem 2005 Apr 1;280(13):12766-73 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:97900

Associated
Alleles

Symbol	Name
Myc^tm1Lbox	myelocytomatosis oncogene; targeted mutation 1, Linda M Boxer

Associated
Genotypes

Allelic Composition	Genetic Background
Myc^tm1Lbox/Myc^tm1Lbox	involves: 129S1/Sv * 129X1/SvJ * FVB/N
Myc^tm1Lbox/Myc⁺	involves: 129S1/Sv * 129X1/SvJ * FVB/N

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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