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Phenotype Image Detail
Image
Caption A: Forestomach (FS) carcinoma in a 58 week old male Atp2a2tm1Ges/Atp2a2+ mouse. The glandular stomach (GS) was intact; the tumor extended into the abdominal cavity with severe inflammation, necrosis, and adhesion to adjacent tissues, including spleen (Sp). B: Forestomach carcinoma in a 76 week old male. Inset, gross appearance of stomach with multiple lesions of forestomach and no lesions of glandular stomach. C: Forestomach carcinoma in a 68 week old male with extenstive keratinization (arrows). D: Multifocal papillomas (arrows) in forestomach of a 75 week old male. E: Monderately dysplastic papilloma in esophagus of a 66 week old male. F: squamous cell carcinoma (SCC) of the tongue of a 75 week old male; the palette (P) was retracted upwards to show lesion at base of tongue (T). G: Carcinoma of the tongue of a 58 week old male. H: Papilloma of the tongue of a 66 week old male. I: Carcinoma of the oral mucosa (cheek) of a 76 week old male. J: Skin carcinoma on the jaw of a 65 week old female. K: Skin carcinoma in large, abscessed lesion from below the right ear of a 74 week old male. L: Skin carcinoma on penis of a 66 week old male. Scale bars: B, E, G, H and K, 100um; I, 200um; C, D and J, 500um; L, 1mm.
Copyright This image is from Liu LH, J Biol Chem 2001 Jul 20;276(29):26737-40 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:69754
Associated
Alleles
Symbol Name
Atp2a2tm1Ges ATPase, Ca++ transporting, cardiac muscle, slow twitch 2; targeted mutation 1, Gary E Shull

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory