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| Caption | A: Litter of newborn mice with three Pex2tm1Plf/Pex2tm1Plf mice (top row) and four control mice (bottom row). Note the absence of milk in the stomach and variable size in the mutant mice. Abnormal facies are not evident in the mutant mice. B-H: Alcian blue (cartilage) and alizarin red (bone) staining of newborn mouse calvarium. The weight of each mouse is shown. B: Typical appearance of the calvarium in control mice (70%). f, frontal bone; p, parietal bone; ip, interparietal bone. C: Control mouse with slightly open "anterior fontanelle: but relatively normal bone density (19%). D: Runted, control mouse showing slight enlargement of fontanelle space and reduced bone density in medial frontal and interparietal bone. E-H: Mutant mice, demonstarting the correlation of increasing severity in reduction of bone density in frontal and interparietal bones and enlargement of fontanelle spaces with decreasing size of the mouse. Scale bars: 1cm. | ||||
| Copyright | This image is from Faust PL, J Cell Biol 1997 Dec 1;139(5):1293-305, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:44975 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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