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Phenotype Image Detail
Image
Caption Electron micrographs of wild type and Slc12a3tm1Ges/Slc12a3tm1Ges distal convoluted tubule cells. Relative to the mitochondria in wild type cells (A), mitochondria in Slc12a3tm1Ges/Slc12a3tm1Ges cells (B) appear to be reduced in number and less elongated in shape. Cells of both genotypes have extensive basolateral membrane folds, but the membrane folds are more closely associated with the mitochondria in wild type cells than in mutant cells. Scale bar: 5um.
Copyright This image is from Schultheis PJ, J Biol Chem 1998 Oct 30;273(44):29150-5 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:50596
Associated
Alleles
Symbol Name
Slc12a3tm1Ges solute carrier family 12, member 3; targeted mutation 1, Gary E Shull
Associated
Genotypes
Allelic Composition Genetic Background
Slc12a3tm1Ges/Slc12a3tm1Ges Not Specified

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory