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| Caption | Histology of toluidine blue-stained sections of oxyntic gastric glands from wild type and Atp4atm1Ges/Atp4atm1Ges stomach. A: Composite image of gastric glands from the corpus of an adult wild type stomach. Typical parietal cells are indicated by arrows. Chief cells with characteristic secretory granules were present at the base of the glands (arrowheads). B: Chief cells (arrowheads) and parietal cells (arrows) were also present in adult Atp4atm1Ges/Atp4atm1Ges gastric glands. Parietal cells had either numerous vacuole-like dilations (top arrow) or a single large dilation (bottom arrow). C: Severely dysplastic gastric glands from an adult mutant mouse, with chief cells (arrowhead), parietal cells with cytoplasmic dilations (arrow), and a large cyst surrounded by a single layer of a low cuboidal epithelium (double arrow). Scale bar: 50um. | ||||
| Copyright | This image is from Spicer Z, J Biol Chem 2000 Jul 14;275(28):21555-65 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:63470 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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