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| Caption | Progression of pulmonary histopathology in Sftpctm1Swg/Sftpctm1Swg mice. Lungs were obtained from wild type littermates (A,C and E) or mutant (B,D and F) mice. Lungs were inflation-fixed at 20 cm H2O of pressure and stained with hematoxylin and eosin. Extensive airspace remodeling, stromal thickening, and monocytic infiltration were noted at 2 months (B), 6 months (D), and 12 months (F) of age. Perivascular and peribronchiolar mononuclear infiltrates and epithelial cell dysplasia in conducting airways are shown in F. Micrographs x625 are representative of at least 3-5 mice of similar ages. | ||||
| Copyright | This image is from Glasser SW, J Biol Chem 2003 Apr 18;278(16):14291-8 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:82925 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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