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| Caption | A: Eyelids from a 2 day old wild type mouse. f, fused eyelid epidermis; c, cornea. B: Eyelids from Dsc1tm1Dga/Dsc1tm1Dga littermate showing a failure of eyelid fusion, inflammation, and corneal damage. t, eyelid tips which have failed to fuse. C: Flaky skin in two mutant mice at 2 days old. At this age, mutant mice were indistinguishable in size from their normal littermates. D: Flaky skin and characteristic runted appearance in an 8 day old mutant mouse (bottom) when compared with a wild type littermate (top). E: Delayed weight gain in mutant mice. Results from a typical litter consisting of nine pups in which a mutant (Nu) mouse and its wild type (No) littermates were born with equal weights, but at weaning (21 days) the mutant mouse weighed 30% less than the average of the others. Bars represent range of weights of normal littermates. 10 litters were examined with similar results. Bars, 150um. | ||||
| Copyright | This image is from Chidgey M, J Cell Biol 2001 Nov 26;155(5):821-32, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:73102 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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