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| Caption | Ultrastructural analysis of podocytes from control and Lmx1btm1Rjo/Lmx1btm1Rjo mice. Low and high-magnification micrographs from control (a and b) and Lmx1btm1Rjo/Lmx1btm1Rjo (d and e) mice show reduced foot process formation in the mutant. Those processes that do form have aberrant cell-cell junctions (f, arrows). Normal and aberrant processes and junctions have been schematized for clarity (insets in b and f). Mutant podocytes resemble those observed in immature control glomeruli (c), suggesting that mutant podocytes are developmentally arrested. P, podocyte; rbc, red blood cell; E, endothelial cell; arrowheads, foot processes. Bar: a, c, and d, 2.3um; b, e and f, 0.7um. | ||||
| Copyright | This image is from Miner JH, J Clin Invest 2002 Apr;109(8):1065-72 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76089 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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