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Phenotype Image Detail
Image
Caption A: Gomori trichrom staining of cryostat section of the heart from a Lama4tm1Ktry/Lama4tm1Ktry mouse showing multiple foci of fibrosis in right and left ventricular wall, interventricular septum, right and left atria, and A-V node region (arrows). B: High power magnification of A-V node region showing cardiomyocyte degeneration and fibrosis. C: Enzyme histochemical staining for acetylcholine esterase to highlight the A-V node (AVN). D: High power magnification of a degenerative region from interventricular septum (IVS) showing cardiomyocyte degeneration and fibrosis. Scale bars: B-D, 100um.
Copyright This image is from Wang J, J Biol Chem 2006 Jan 6;281(1):213-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:105789
Associated
Alleles
Symbol Name
Lama4tm1Ktry laminin, alpha 4; targeted mutation 1, Karl Tryggvason
Associated
Genotypes
Allelic Composition Genetic Background
Lama4tm1Ktry/Lama4tm1Ktry B6.129X1-Lama4tm1Ktry

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory