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Phenotype Image Detail
Image
Caption A: Histological sections of quadriceps muscle, footpad and ear of 14 week old male wild-type (WT) and Syt7tm1Nan/Syt7tm1Nan (KO) mice. Increased accumulation of connective tissue is evident in the sections of mutant mice. Skeletal muscle sections are stained with toluidine blue, footpad sections with hematoxylin and eosin and skin sections with Masson's trichrome, which stains collagen fibers in blue. Bars, 100um. B: Toluidine blue-stained sections of quadriceps muscle from male wild-type and mutant mice at 4, 8 and 44 weeks old. Infiltration of inflammatory cells is initially detected (black arrows), followed by tissue injury, fiber invasion by phagocytic cells (white arrow), and collagen deposition (black arrowheads). Bars, 25um.
Copyright This image is from Chakrabarti S, J Cell Biol 2003 Aug 18;162(4):543-9, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:85201
Associated
Alleles
Symbol Name
Syt7tm1Nan synaptotagmin VII; targeted mutation 1, Norma W Andrews
Associated
Genotypes
Allelic Composition Genetic Background
Syt7tm1Nan/Syt7tm1Nan involves: 129S1/Sv * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory