Phenotype Image Detail

Image

Caption

A: Lined appearance on skin surface on the lateral trunk of Asprv1^tm1Tmts/Asprv1^tm1Tmts (-/-) mice. Static state of 14 week old female Asprv1^tm1Tmts/Asprv1⁺ (+/-) and Asprv1^tm1Tmts/Asprv1^tm1Tmts mice (upper panel). In homozygous mutant mice, lined grooves appear parallel to the body axis. These grooves were more enhanced by stretching the hind legs backwards (lower panel). B: Wrinkle formation in homozygous mutant mice. The hair of 6 week old male heterozygous and homozygous mutant mice were removed. After removal of the hair, the wrinkles appear on the surface of the skin only in the homozygous mutant mice when hanged by the tail.

This image is from Matsui T, J Biol Chem 2006 Sep 15;281(37):27512-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:116504

Associated
Alleles

Symbol	Name
Asprv1^tm1Tmts	aspartic peptidase, retroviral-like 1; targeted mutation 1, Takeshi Matsui

Associated
Genotypes

Allelic Composition	Genetic Background
Asprv1^tm1Tmts/Asprv1^tm1Tmts	involves: 129S4/SvJae * C57BL/6

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