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| Caption | A: Structurally abnormal sperm tails in Vdac3tm1Wjc/Vdac3tm1Wjc male mice. Shown is an electron micrograph of axonemes from epididymal sperm of wild-type (VDAC3(+/+), C) (x10,000) and mutant (VDAC3(-/-), A) (x13,000). The arrows indicate the position of the missing microtubules. The lower panels show lengthwise images (x6,000) of the midpiece of elongating spermatids, demonstrating the enlarged, disordered mitochondria of mutant spermatids (B) in comparison with the orderly spiral of mitochondria from wild-type spermatids (D). B: Tracheal cilia are strucutrally normal. The top panels show cross-sections through tracheal epithelial cilia from wild-type (A) and mutant mice (B) (x26.000). The bottom panel shows representative scanning electron micrographs (x2000) from the same tracheal epithelia. Note the paucity of ciliated cells from mutant mice (D). | ||||
| Copyright | This image is from Sampson MJ, J Biol Chem 2001 Oct 19;276(42):39206-12 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:72188 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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