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| Caption | Wild-type (A) embryo at E12.5 reveals yolk sac with well developed blood islands, while Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr littermate (B) is smaller in size with fewer blood islands in its yolk sac (ys). C: External appearance of eye, blood-enriched liver, and distal part of hind limb with separated fingers (white arrow) in wild-type embryo. B: Mutant embryo shows dilated leaking small vessels (white arrowhead) and few large blood vessels. Pigmented tissue is thinner in the dorsal portion of the eye (ey). The liver (li) mass is small and pale in the mutant embryo. Finger separation does not occur in the distal part of hind limb (white arrow). Each pair of photographs was taken at the same magnification. | ||||
| Copyright | This image is from Zhu YJ, J Biol Chem 2003 Jan 17;278(3):1986-90 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:81217 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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