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Phenotype Image Detail
Image
Caption Phenotype of wild-type and Eif2ak4tm1Drc/Eif2ak4tm1Drc mice fed a leucine-devoid diet for 6 days. Wild-type (GCN2+/+ -LEU, left) and Eif2ak4tm1Drc/Eif2ak4tm1Drc (GCN2-/-HH -LEU, right) mice. Mutant mice appeared scruffy and lethargic in appearance following the leucine-deficient diet.
Copyright This image is from Anthony TG, J Biol Chem 2004 Aug 27;279(35):36553-61 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:92545
Associated
Alleles
Symbol Name
Eif2ak4tm1Drc eukaryotic translation initiation factor 2 alpha kinase 4; targeted mutation 1, Douglas R Cavener
Associated
Genotypes
Allelic Composition Genetic Background
Eif2ak4tm1Drc/Eif2ak4tm1Drc involves: 129S6/SvEvTac * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory