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Phenotype Image Detail
Image
Caption The fourth pair of mammary glands was isolated, fixed and whole-mounted from 5 week old (A and B), 10 week old (C-F), 15 week old (G and H) wild type or Ncoa6tm1Jkr/Ncoa6tm1Jkr Tg(MMTV-cre)FMam/? mice. Note that the PRIP deficiency (B,D,F and H) caused defective branching from early puberty (B) to the end of puberty (D,F) and persisted after puberty (H). E and F represent higher magnification of the gland structures in panels C and D, respectively.
Copyright This image is from Qi C, J Biol Chem 2004 Aug 6;279(32):33696-701 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:121207
Associated
Alleles
Symbol Name
Ncoa6tm1Jkr nuclear receptor coactivator 6; targeted mutation 1, Janardan K Reddy
Tg(MMTV-cre)FMam transgene insertion F, Lothar Hennighausen
Associated
Genotypes
Allelic Composition Genetic Background
Ncoa6tm1Jkr/Ncoa6tm1Jkr
Tg(MMTV-cre)FMam/?
involves: 129P2/OlaHsd * FVB

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory