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Phenotype Image Detail
Image
Caption A: Phenotypes of 18 day old Calrtm1Mlk/Calr+ (crt+/-) and Calrtm1Mlk/Calrtm1Mlk (crt-/-) mouse fetuses are shown. The arrow indicates the umbilical hernia. Leg and tail biopsies were removed for better visualization of the defect and were used for DNA and protein analysis. B: Low magnification histology of 18 day old heterozygous and homozygous embryos are show. The arrow indicates the umbilical hernia. C: Phenotypes of wild-type (wt) and homozygous 12.5 day old mouse embryos. Sagittal sections of embryos were stained with hematoxylin and eosin.
Copyright This image is from Mesaeli N, J Cell Biol 1999 Mar 8;144(5):857-68, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:53466
Associated
Alleles
Symbol Name
Calrtm1Mlk calreticulin; targeted mutation 1, Marek Michalak
Associated
Genotypes
Allelic Composition Genetic Background
Calrtm1Mlk/Calrtm1Mlk involves: 129S4/SvJae * C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory