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Phenotype Image Detail
Image
Caption Controls are on the left and Lama5tm1Jhm/Lama5tm1Jhm mutants are on the right. A and B: Whole mount dorsal views of E14.5 fore- and hindlimbs. Digits 1 and 5 are partially septated in the mutant hindlimb. C and D:. Alcian blue staining at E13.5 demonstrates proper patterning in the mutant. Digits 2 and 3 are closely apposed but are not fused (arrows). E and F: Alcian blue staining at E15.5 shows complete fusion of mutant digits 2 and 3 (arrows) and the absence of distal phalanges from digits 2-4 in the mutant forelimb.
Copyright This image is from Miner JH, J Cell Biol 1998 Dec 14;143(6):1713-23, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:51557
Associated
Alleles
Symbol Name
Lama5tm1Jhm laminin, alpha 5; targeted mutation 1, Jeffrey H Miner
Associated
Genotypes
Allelic Composition Genetic Background
Lama5tm1Jhm/Lama5tm1Jhm involves: 129 * C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory