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Phenotype Image Detail
Image
Caption Phenotype of Fdft1tm1Yma/Fdft1tm1Yma embryos. A: An E9.5 wild-type embryo with normal developmental morphology. B: An E9.5 Fdft1tm1Yma/Fdft1tm1Yma embryo that lacked somite structure. C: An E9.5 mutant embryo that was much smaller than wild-type embryos but apparently almost normal except for an undeveloped forebrain. D: E10.5 mutant embryos that had open heads (indicated by white arrows). Bar, 1 mm. E: A sagittal section of an E9.5 wild-type embryo as a normal control. F: A sagittal section of an E10.5 mutant embryo that is shown in D. The unclosed head is indicated by an arrow. G: Microscopic examination of a part of the head that is shown in F. Some of the cells with condensed nuclei are indicated by white arrows. Hematoxylin eosin staining was used.
Copyright This image is from Tozawa R, J Biol Chem 1999 Oct 22;274(43):30843-8 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:58231
Associated
Alleles
Symbol Name
Fdft1tm1Yma farnesyl diphosphate farnesyl transferase 1; targeted mutation 1, Nobuhiro Yamada
Associated
Genotypes
Allelic Composition Genetic Background
Fdft1tm1Yma/Fdft1tm1Yma involves: 129S7/SvEvBrd

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory