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Phenotype Image Detail
Image
Caption Histology of thymus of Zeb1tm1Yhi/Zeb1tm1Yhi mice. Thymi of 6 week old Zeb1tm1Yhi/Zeb1+ (A and C) and Zeb1tm1Yhi/Zeb1tm1Yhi (B and D) mice were fixed in Bouin's fixative and stained with hematoxylin and eosin. The heterozygous thymus had developed distinct medulla and cortex (A), while mutant thymi had uniform parenchyma with light staining as seen in medulla of the heterozygous thymus (B). Note also the differences of size and cellularity between them. The heterozygous thymus had a typical cortex which consists of the densely packed and actively proliferating small thymocytes as shown in higher magnification (C), while the mutant thymus seemed to lack its architecture (D). Bars: A and B, 200 um; C and D, 40 um.
Copyright This image is from Higashi Y, J Exp Med 1997 Apr 21;185(8):1467-79, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:39865
Associated
Alleles
Symbol Name
Zeb1tm1Yhi zinc finger E-box binding homeobox 1; targeted mutation 1, Yujiro Higashi
Associated
Genotypes
Allelic Composition Genetic Background
Zeb1tm1Yhi/Zeb1tm1Yhi B6.129P2-Zeb1tm1Yhi

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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory