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Caption | A and B: Photographs of 17 day old wild-type (Lmna+/+, A) and Lmnatm1Lgf/Lmnatm1Lgf (LmnaHG/HG, B) mice. The mutant mouse had a spontaneous fracture in the left forelimb (red arrow). C-F: Surface renderings of microCT scans of the skull (performed at exactly the same threshold) for a 17 day old mutant mouse (D and F) and littermate wild-type mouse (C and E). C and D: Top view of skulls. The mutant skull is misshapen, poorly mineralized, and exibits incomplete fusion of the cranial sutures (red arrow). E and F: Lateral view of skulls. The mutant skull is misshapen, with a small mandible (upper red arrow) and a short lower incisor (lower left arrow). | ||||
Copyright | This image is from Yang SH, J Clin Invest 2006 Aug;116(8):2115-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:113119 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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