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Phenotype Image Detail
Image
Caption Gross morphology of Portm1Cbk/Portm1Cbk embryos reveals a spectrum of abnormalities. The asterisk indicates the boundaries of the open neural tube. The arrow indicates bleeding along the neural folds. Arrowhead, the enlarged pericardial cavity. fb, forebrain; mb, midbrain; hb, hindbrain; ba, branchial arches; h, heart; t, tail; hl, hind limb bud; fl, fore limb bud. A, wild-type (+/+) embryo; B, Type I Portm1Cbk/Portm1Cbk (-/-) embryo; C, Type II mutant embryo.
Copyright This image is from Shen AL, J Biol Chem 2002 Feb 22;277(8):6536-41 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74666
Associated
Alleles
Symbol Name
Portm1Cbk cytochrome p450 oxidoreductase; targeted mutation 1, Charles B Kasper
Associated
Genotypes
Allelic Composition Genetic Background
Portm1Cbk/Portm1Cbk involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory