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Phenotype Image Detail
Image
Caption Phenotypic analysis of Ugt1tm1Rhtu/Ugt1tm1Rhtu mice. A: As early as 8 hours after birth, the elevated concentrations of unconjugated serum bilirubin are displayed in neonatal mice as jaundice and easily identified by skin color. A litter generated from crossing Ugt1tm1Rhtu/Ugt1+ mice shows a single Ugt1tm1Rhtu/Ugt1tm1Rhtu (Ugt1-/-) neonatal mouse with littermates that are either heterozygous or wild-type. The appearance of jaundice is also contrasted in a side by side photograph. B: Life span of 18 neonatal mutant mice. The majority of the mice die before day 7.
Copyright This image is from Nguyen N, J Biol Chem 2008 Mar 21;283(12):7901-11 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:133790
Associated
Alleles
Symbol Name
Ugt1tm1Rhtu UDP glucuronosyltransferase 1 complex; targeted mutation 1, Robert H Tukey
Associated
Genotypes
Allelic Composition Genetic Background
Ugt1tm1Rhtu/Ugt1tm1Rhtu involves: 129 * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory