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| Caption | A: Histological views of wild-type (a-c) and Epb41l5tm1Sia/Epb41l5tm1Sia (EBP41L5-/-) (a'-c') embryos at E6.5 (a and a'), E7.5 (b and b') and E8.5 (c and c'), respectively. (a, a' and b, and b') Horizontal sections. (c and c') Sagittal sections. Anterior is to the left. Bars, 100um. C: Electron microscopic views of mutant embryos. (a-j) Views in wild-type. (a'-j') Views in mutant embryos. (a and a') Views at E6.5 primitive streak. (b and b') Enlarged views of the regions boxed in a and a', respectively. (c and c') Views of the lateral region of E6.5 embryos. (d and d') Views of the anterior region of E7.5 embryos. (e-f') Enlarged views of the regions boxed in d and d'. (g and g') Views of laterally invaginated E7.5 mesoderm cells. (h and h') Views of cells invaginating at E7.5 primitive streak. (I and i') Enlarged views of the regions boxed in (h and h'). (j and j') Views of E7.5 endoderm cells. Dotted lines in d and d' outline individual cells in the anterior-most ectoderm layers; these cells are ectodermal, as suggested by the location of residual basement membrane components and E-cadherin expression shown in Fig. 4, b' and c'. Arrows in f and j indicate basement membranes. In e and e', TJ is tight junction; AJ, adherens junction; De, desmosome. Bars, 5 um. | ||||
| Copyright | This image is from Hirano M, J Cell Biol 2008 Sep 22;182(6):1217-30, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:142596 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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