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Phenotype Image Detail
Image
Caption Phenotypes of wild-type and Pkp2tm1Wbm/Pkp2tm1Wbm (PKP2-/-) embryos at E10.75. A and B: External appearance of embryos. In the Pkp2tm1Wbm/Pkp2tm1Wbm embryo, blood has accumulated in the pericardial and peritoneal cavities, which are connected at the embryonal stage. C-F: The vasculature of the yolk sac contains red blood cells in the wild-type (WT), but not in the mutant embryos, as shown by whole-mount photography (C and D) and microscopy of hematoxylin and eosin-stained sections of endothelia (E and F). Bars: 1000um, A,B,C,D; 100um, E and F.
Copyright This image is from Grossmann KS, J Cell Biol 2004 Nov 11;167(1):149-60, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:93314
Associated
Alleles
Symbol Name
Pkp2tm1Wbm plakophilin 2; targeted mutation 1, Walter Birchmeier
Associated
Genotypes
Allelic Composition Genetic Background
Pkp2tm1Wbm/Pkp2tm1Wbm involves: C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory