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| Caption | Radiographs of the skeletal abnormalities in 7 month old Smad3tm1Cxd/Smad3tm1Cxd (-/-) mice. A and B: Whole-mount view of wild-type (+/+) and mutant skeletons. Mutant mice exhibited increased intensities in vertebral and knee joints (arrowheads). C-H: Enlarged views of knee (C and D), vertebral (E and F), and sternum joints (G and H). The increased density in mutant joints is caused by formation of extra bones (arrowheads). However, decreased bone densities were found in other areas of mutant bones compared with corresponding regions of wild-type mice. | ||||
| Copyright | This image is from Yang X, J Cell Biol 2001 Apr 2;153(1):35-46, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:68792 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/05/2024 MGI 6.24 |
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