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Phenotype Image Detail
Image
Caption Phenotypic analysis of Wwoxtm1Ria/Wwoxtm1Ria mice. Impaired growth is shown in A. Three-week old mice showing significant small size of Wwoxtm1Ria/Wwoxtm1Ria (HO) mouse compared with wild-type (WT) and Wwoxtm1Ria/Wwox+ (HET) mice. B: Growth curves of wild-type, heterozygous and mutant mice. Newborn pups were weighed every day from day 1. Mice were then genotyped, and weights were plotted on growth curve. The weights of mutant mice diverge after day 3 from that of the wild-type and heterozygous mice. C: Radiography of femurs of 3 week old mice showing smaller but also less dense bone of the mutant mouse. D: Alizarin red/Alcian blue staining of newborn skeletons.
Copyright This image is from Aqeilan RI, J Biol Chem 2008 Aug 1;283(31):21629-39 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:138140
Associated
Alleles
Symbol Name
Wwoxtm1Ria WW domain-containing oxidoreductase; targeted mutation 1, Rami I Aqeilan
Associated
Genotypes
Allelic Composition Genetic Background
Wwoxtm1Ria/Wwoxtm1Ria involves: 129X1/SvJ * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory