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Phenotype Image Detail
Image
Caption Analysis of placenta. A-D: DAPI-stained sections of placentae from E10.5 wild-type (A and C) and Mfn2tm1Dcc/Mfn2tm1Dcc (B and D) littermate embryos. The boxed areas of A and B are enlarged in C and D. Arrows and arrowheads indicate trophoblast giant cells. Note that the giant cells in D are sparser and have smaller nuclei. E and F: Hematoxylin-eosin stained sections from the placentae above. G and H: PL-I (giant cell marker) RNA in situ analysis of placentae from E9.5 wild-type (G) and mutant (H) littermates.
Copyright This image is from Chen H, J Cell Biol 2003 Jan 21;160(2):189-200, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:81438
Associated
Alleles
Symbol Name
Mfn2tm1Dcc mitofusin 2; targeted mutation 1, David C Chan
Associated
Genotypes
Allelic Composition Genetic Background
Mfn2tm1Dcc/Mfn2tm1Dcc involves: 129S/SvEv

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory