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| Caption | A: Newborn Mbtps1tm1Jdh/Mbtps1tm1Jdh Tg(Col2a1-cre)1Bhr/0 (S1Pcko, right) mice exhibit severe chondrodysplasia as compared with wild-type mice (WT, left). B: Mutant mice have a smaller skull and foreshortened mandibles, which results in the protrusion of the tongue. C: Whole animal skeletal preparation of wild-type (left) and mutant (right) newborns. D: The skeletal patterning in mutant mice is similar to wild-type mice, but all the skeletal elements are smaller. The arrow points to the furrow that is formed in mutant skull (absent in wild-type) during skeletal staining, which suggests a lack of structural integrity of the skull bones. | ||||||
| Copyright | This image is from Patra D, J Cell Biol 2007 Nov 19;179(4):687-700, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:135374 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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