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Phenotype Image Detail
Image
Caption Histologic sections of yolk sac visceral endoderm from wild-type and Apobtm3Sgy/Apobtm3Sgy embryos. Embryos were dissected in PBS. Portions of the yolk sac membranes were removed for genotype analysis by Southern blotting, and the remainder was fixed in 4% paraformaldehyde. Fixed embryos were embedded in paraffin and sectioned using standard techniques; sections were stained with hematoxylin and eosin. Sections from wild-type (+/+, A) and Apobtm3Sgy/Apobtm3Sgy (-/-, B) yolk sacs are shown. A layer of yolk sac visceral endodermal cells is visible overlying the embryonic mesoderm and blood islands, with the apical surface of these cells facing the maternal tissues. The arrows indicate vacuoles at the basal aspect of the visceral endodermal cells in the mutant yolk sacs. Magnification, 200x.
Copyright This image is from Farese RV Jr, J Lipid Res 1996 Feb;37(2):347-60 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text is from JLR. J:84977
Associated
Alleles
Symbol Name
Apobtm3Sgy apolipoprotein B; targeted mutation 3, Stephen G Young
Associated
Genotypes
Allelic Composition Genetic Background
Apobtm3Sgy/Apobtm3Sgy involves: 129S7/SvEvBrd * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory